Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665275 | 0.91 | GCK (0.47) | KCNH2GCK | |
| SCHEMBL2665262 | 0.90 | GCK (0.48) | KCNH2GCK | |
| SCHEMBL9072573 | 0.89 | GCK (0.47) | KCNH2GCK | |
| SCHEMBL2665280 | 0.88 | GCK (0.47) | KCNH2GCK | |
| SCHEMBL2665276 | 0.88 | KCNH2 (0.45) | KCNH2GCK | |
| SCHEMBL9072584 | 0.87 | KCNH2 (0.61) | KCNH2GCK | |
| SCHEMBL2665334 | 0.87 | KCNH2 (0.61) | KCNH2GCK | |
| SCHEMBL9072614 | 0.86 | GCK (0.45) | KCNH2GCK | |
| SCHEMBL2665294 | 0.86 | GCK (0.46) | KCNH2GCK | |
| SCHEMBL9072556 | 0.86 | GCK (0.46) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132425-B2 | 5-substituted-six-membered heteroaromatic glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2006-11-07 | — | — | US | disclosed |