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Sugi Predict / Compounds / SCHEMBL2665402

SCHEMBL2665402

SCHEMBL2665402

NC/N=C(/Nc1ccc(OC(F)(F)F)cc1)N(Cc1ccc(C(=O)Nc2nn[nH]n2)cc1)c1ccc(C2CCCCC2)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GCGR P47871 20/20 0.60
▸ GIPR P48546 7/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665398 0.90 GCGR (0.58) GCGRGIPR
SCHEMBL4082056 0.90 GCGR (0.69) GCGRGIPR
SCHEMBL2665442 0.88 GCGR (0.50) GCGRGIPR
SCHEMBL4091739 0.87 GCGR (0.60) GCGRGIPR
SCHEMBL2665403 0.86 GCGR (0.53) GCGRGIPR
SCHEMBL2663127 0.86 GCGR (0.64) GCGRGIPR
SCHEMBL4086952 0.86 GCGR (0.59) GCGRGIPR
SCHEMBL4091962 0.86 GCGR (0.60) GCGRGIPR
SCHEMBL2665406 0.85 GCGR (0.52) GCGRGIPR
SCHEMBL2665457 0.85 GCGR (0.47) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 — — WO disclosed