Sugi Predict

Sugi Predict / Compounds / SCHEMBL2665403

SCHEMBL2665403

SCHEMBL2665403

NC/N=C(/Nc1ccc(OC(F)(F)F)cc1)N(Cc1ccc(C(=O)Nc2nn[nH]n2)cc1)c1ccc(C2=CCCCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GCGR P47871 20/20 0.53
▸ GIPR P48546 10/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9070984 0.93 GCGR (0.53) GCGRGIPR
SCHEMBL2665396 0.93 GCGR (0.55) GCGRGIPR
SCHEMBL4085303 0.90 GCGR (0.62) GCGRGIPR
SCHEMBL2665452 0.88 GCGR (0.49) GCGRGIPR
SCHEMBL2665402 0.86 GCGR (0.60) GCGRGIPR
SCHEMBL2665407 0.85 GCGR (0.53) GCGRGIPR
SCHEMBL2665451 0.85 GCGR (0.56) GCGRGIPR
SCHEMBL2663504 0.85 GCGR (0.55) GCGRGIPR
SCHEMBL2665397 0.85 GCGR (0.53) GCGRGIPR
SCHEMBL2665447 0.83 GCGR (0.60) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 — — WO disclosed