SCHEMBL2665415

SCHEMBL2665415

O=C(Nc1nn[nH]n1)c1ccc(CN(/C(=C\[N+](=O)[O-])Nc2cc(Cl)cc(Cl)c2)c2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GCGR P47871 17/20 0.51
GIPR P48546 8/20 0.51
GCG P01275 1/20 0.39
STAT3 P40763 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4091983 0.88 GCGR (0.65) GCGRGIPR
SCHEMBL2665412 0.87 GCGR (0.47) GCGRGIPRGCG
SCHEMBL2665405 0.86 GCGR (0.52) GCGRGIPRGCG
SCHEMBL2665395 0.86 GCGR (0.58) GCGRGIPR
SCHEMBL2665418 0.85 GCGR (0.50) GCGRGIPRGCG
SCHEMBL2665404 0.85 GCGR (0.53) GCGRGIPRGCGSTAT3
SCHEMBL2665406 0.83 GCGR (0.52) GCGRGIPRGCGSTAT3
SCHEMBL2665365 0.82 GCGR (0.64) GCGRGIPR
SCHEMBL4092390 0.82 GCGR (0.55) GCGRGIPRGCG
SCHEMBL9071007 0.82 GCGR (0.50) GCGRGIPRGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed