SCHEMBL9071007

SCHEMBL9071007

O=C(Nc1nn[nH]n1)c1ccc(CN(/C(=N\CC(F)(F)F)Nc2cc(Cl)cc(Cl)c2)c2ccc(C3CCCCC3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.50
GIPR P48546 12/20 0.50
GCG P01275 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665406 0.91 GCGR (0.52) GCGRGIPRGCG
SCHEMBL2665404 0.89 GCGR (0.53) GCGRGIPRGCG
SCHEMBL2665378 0.89 GCGR (0.47) GCGRGIPRGCG
SCHEMBL4091983 0.87 GCGR (0.65) GCGRGIPR
SCHEMBL9071003 0.86 GCGR (0.51) GCGRGIPR
SCHEMBL9070954 0.86 GCGR (0.48) GCGRGIPRGCG
SCHEMBL2665442 0.85 GCGR (0.50) GCGRGIPRGCG
SCHEMBL9071002 0.83 GCGR (0.60) GCGRGIPR
SCHEMBL4092390 0.82 GCGR (0.55) GCGRGIPRGCG
SCHEMBL2665457 0.82 GCGR (0.47) GCGRGIPRGCG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed