Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.54 |
| ▸ | GIPR | P48546 | 15/20 | 0.54 |
| ▸ | GLP1R | P43220 | 4/20 | 0.54 |
| ▸ | GCG | P01275 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665407 | 0.93 | GCGR (0.53) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL4091776 | 0.90 | GCGR (0.67) | GCGRGIPRGLP1R | |
| SCHEMBL9071003 | 0.89 | GCGR (0.51) | GCGRGIPRGLP1RMGAT2 | |
| SCHEMBL2665404 | 0.85 | GCGR (0.53) | GCGRGIPRGCG | |
| SCHEMBL2665396 | 0.85 | GCGR (0.55) | GCGRGIPR | |
| SCHEMBL2665405 | 0.85 | GCGR (0.52) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663522 | 0.83 | GCGR (0.67) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2665452 | 0.82 | GCGR (0.49) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663564 | 0.82 | GCGR (0.52) | GCGRGIPRGLP1RGCGMGAT2 | |
| SCHEMBL2663158 | 0.81 | GCGR (0.54) | GCGRGIPRGLP1RGCGMGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051357-A1 | GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |