SCHEMBL2665396

SCHEMBL2665396

N/N=C(/Nc1ccc(OC(F)(F)F)cc1)N(Cc1ccc(C(=O)Nc2nn[nH]n2)cc1)c1ccc(C2=CCCCC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.55
GIPR P48546 9/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2665403 0.93 GCGR (0.53) GCGRGIPR
SCHEMBL9070984 0.92 GCGR (0.53) GCGRGIPR
SCHEMBL4085303 0.91 GCGR (0.62) GCGRGIPR
SCHEMBL2663504 0.86 GCGR (0.55) GCGRGIPR
SCHEMBL2665397 0.86 GCGR (0.53) GCGRGIPR
SCHEMBL2665417 0.85 GCGR (0.54) GCGRGIPR
SCHEMBL9072954 0.83 GCGR (0.52) GCGRGIPR
SCHEMBL2663489 0.82 GCGR (0.52) GCGRGIPR
SCHEMBL13800746 0.82 GCGR (0.52) GCGRGIPR
SCHEMBL13800749 0.82 GCGR (0.51) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003051357-A1 GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed