Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.60 |
| ▸ | GIPR | P48546 | 9/20 | 0.60 |
| ▸ | GLP1R | P43220 | 3/20 | 0.59 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.51 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.51 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.51 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.51 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.51 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.51 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.51 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070956 | 0.93 | GCGR (0.60) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665450 | 0.89 | GCGR (0.62) | GCGRGIPRGLP1R | |
| SCHEMBL2665380 | 0.88 | GCGR (0.63) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665391 | 0.87 | GCGR (0.61) | GCGRGIPRGLP1R | |
| SCHEMBL2665454 | 0.86 | GCGR (0.80) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665387 | 0.84 | GCGR (0.78) | GCGRGIPRGLP1R | |
| SCHEMBL2655596 | 0.84 | GCGR (0.67) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665388 | 0.84 | GCGR (0.64) | GCGRGIPRGLP1R | |
| SCHEMBL2665427 | 0.84 | GCGR (0.59) | GCGRGIPRGLP1RADCY6ADCY3 | |
| SCHEMBL2665403 | 0.83 | GCGR (0.53) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051357-A1 | GLUCAGON RECEPTOR ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |