Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.63 |
| ▸ | GIPR | P48546 | 15/20 | 0.63 |
| ▸ | GLP1R | P43220 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665618 | 0.92 | GCGR (0.75) | GCGRGIPRGLP1R | |
| SCHEMBL2665464 | 0.92 | GCGR (0.62) | GCGRGIPRGLP1RLMNASMN1; SMN2 | |
| SCHEMBL2665801 | 0.91 | GCGR (0.67) | GCGRGIPRGLP1R | |
| SCHEMBL2665466 | 0.89 | GCGR (0.60) | GCGRGIPRGLP1R | |
| SCHEMBL6751671 | 0.88 | GCGR (0.66) | GCGRGIPRGLP1RALDH1A1MAPK1 | |
| SCHEMBL9071297 | 0.88 | GCGR (0.55) | GCGRGIPRGLP1RALDH1A1LMNA | |
| SCHEMBL2665614 | 0.87 | GCGR (0.82) | GCGRGIPRGLP1R | |
| SCHEMBL9071762 | 0.86 | GCGR (0.70) | GCGRGIPRGLP1R | |
| SCHEMBL2665459 | 0.86 | GCGR (0.62) | GCGRGIPRALDH1A1LMNAMAPK1 | |
| SCHEMBL9071792 | 0.86 | GCGR (0.69) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000612-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-01-03 | — | — | WO | disclosed |