⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27154415 | 0.88 | BTK (0.32) | — | |
| SCHEMBL26656270 | 0.82 | — | — | |
| SCHEMBL31239975 | 0.81 | PIK3CD (0.34) | — | |
| SCHEMBL31239838 | 0.81 | PIK3CD (0.34) | — | |
| SCHEMBL31239996 | 0.81 | PIK3CD (0.34) | — | |
| SCHEMBL30704241 | 0.81 | PIK3CD (0.34) | — | |
| SCHEMBL26656263 | 0.81 | PIK3CD (0.34) | — | |
| SCHEMBL26949337 | 0.81 | PIK3CD (0.34) | — | |
| SCHEMBL31240060 | 0.80 | GPR119 (0.32) | — | |
| SCHEMBL31239791 | 0.80 | ALOX5AP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270206-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF RAS | NNSA | 2025-08-28 | — | — | US | disclosed |
| WO-2023225252-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF RAS | THERAS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |