SCHEMBL266563

SCHEMBL266563

COc1ccccc1CC(C)N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.64
HTR2A P28223 2/20 0.61
IDO1 P14902 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30249073 1.00 KMT2A (0.64) KMT2AHTR2AIDO1TAAR1
SCHEMBL14655700 1.00 KMT2A (0.64) KMT2AHTR2AIDO1TAAR1
Hydrochloric Acid SCHEMBL28775228 0.98 KMT2A (0.67) KMT2AHTR2AIDO1
Iodide SCHEMBL28548071 0.98 KMT2A (0.62) KMT2AHTR2AIDO1TAAR1
Hydrochloric Acid SCHEMBL30559568 0.98 KMT2A (0.67) KMT2AHTR2AIDO1
SCHEMBL9638844 0.86 IDO1 (0.57) KMT2AIDO1TAAR1
SCHEMBL11946649 0.85 IDO1 (0.52) KMT2AHTR2AIDO1TAAR1
Hydrochloric Acid SCHEMBL5307530 0.84 HTR2A (0.63) HTR2ATAAR1
SCHEMBL878976 0.83 IDO1 (0.53) KMT2AIDO1TAAR1
SCHEMBL23929137 0.83 KMT2A (0.55) KMT2AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101983-A1 NON-STEROIDAL ISONITRILE BINDING COMPOUNDS OF CYTOCHROME P450 SUBTYPES BRANDEIS UNIVERSITY (US) 2025-05-15 WO claimed
CN-116970600-B Nucleic acid extraction method based on magnetic resin 南京诺唯赞生物科技股份有限公司 2025-04-25 CN claimed
CN-119461707-A Method and production system for extracting humic acid and fulvic acid in source water of drinking water 南京大学 2025-02-18 CN claimed
CN-112748991-B Method, apparatus and computer program product for backing up data 伊姆西IP控股有限责任公司 2024-09-13 CN claimed
US-12045140-B2 Live browsing of granular mailbox data COMMVAULT SYSTEMS, INC. (US) 2024-07-23 US claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
US-11809517-B1 Adaptive method of cleaning structural health monitoring data based on local outlier factor SOUTHWEST JIAOTONG UNIVERSITY (CN) 2023-11-07 US claimed
CN-116970600-A Nucleic acid extraction method based on magnetic resin 南京诺唯赞生物科技股份有限公司 2023-10-31 CN claimed
US-20230244572-A1 LIVE BROWSING OF GRANULAR MAILBOX DATA JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2023-08-03 US claimed
CN-116489253-A Network protocol analysis method and related components 上海安恒智慧城市安全技术有限公司 2023-07-25 CN claimed
WO-2013014287-A2 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON AS (NO) 2013-01-31 WO claimed
EP-2551675-A1 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods fo their preparation and their use Chiron AS (NO) 2013-01-30 EP claimed
WO-2007094825-A2 METAXALONE PRODUCTS, METHOD OF MANUFACTURE, AND METHOD OF USE MUTUAL PHARMACEUTICAL COMPANY, INC. (US) 2007-08-23 WO claimed
US-20050032781-A1 Methods for administering active agents to CYP 2D6 sensitive patients ALKERMES, INC. 2005-02-10 US claimed
US-20040224960-A1 Pharmaceutical compositions and methods for their use AGOURON PHARMACEUTICALS, INC. 2004-11-11 US claimed
US-20030144220-A1 Use of CYP2D6 inhibitors in combination therapies PFIZER INC. 2003-07-31 US claimed
EP-1242058-A1 USE OF CYP2D6 INHIBITORS IN COMBINATION THERAPIES Pfizer Products Inc. (US) 2002-09-25 EP claimed
US-20020013372-A1 Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors PFIZER PRODUCTS INC. 2002-01-31 US claimed
EP-1134290-A2 Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors Pfizer Products Inc. (US) 2001-09-19 EP claimed
WO-2000059486-A2 USE OF CYP2D6 INHIBITORS IN COMBINATION THERAPIES PFIZER PRODUCTS INC. (US) 2000-10-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040224960-A1 Pharmaceutical compositions and methods for their use CYP3A5, CYP3A7, CYP3A43 KMT2A 3124/4885HTR2A 2025/4885IDO1 669/4885
US-20030144220-A1 Use of CYP2D6 inhibitors in combination therapies CYP2D6, CYP2B6, CYP3A43 KMT2A 1903/4885HTR2A 565/4885IDO1 185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.