Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.54 |
| ▸ | GIPR | P48546 | 7/20 | 0.53 |
| ▸ | STAT3 | P40763 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2665763 | 0.89 | GCGR (0.49) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2665596 | 0.84 | GCGR (0.58) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL9071337 | 0.84 | GCGR (0.64) | GCGRGIPRSTAT3HDAC6 | |
| SCHEMBL9071334 | 0.84 | GCGR (0.60) | GCGRGIPRSTAT3 | |
| SCHEMBL2665693 | 0.84 | GCGR (0.64) | GCGRGIPRSTAT3HDAC6 | |
| SCHEMBL9071354 | 0.84 | GCGR (0.60) | GCGRGIPRSTAT3 | |
| SCHEMBL2665933 | 0.84 | GCGR (0.62) | GCGRGIPRSTAT3OPRM1OPRK1 | |
| SCHEMBL2665931 | 0.83 | GCGR (0.63) | GCGRGIPRSTAT3 | |
| SCHEMBL2665922 | 0.83 | GCGR (0.61) | GCGRGIPRSTAT3 | |
| SCHEMBL2665923 | 0.83 | GCGR (0.61) | GCGRGIPRSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040446-A1 | GLUCAGON ANTAGONIST/INVERSE AGONIST | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |