Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 18/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CPT2 | P23786 | 1/20 | 0.56 |
| ▸ | CPT1A | P50416 | 1/20 | 0.56 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26410125 | 0.93 | IDH1 (0.64) | IDH1THRBCPT2CPT1ACPT1B | |
| SCHEMBL26672880 | 0.91 | IDH1 (0.53) | IDH1CPT2CPT1ACPT1B | |
| SCHEMBL26656980 | 0.90 | IDH1 (0.73) | IDH1THRBCPT2CPT1ACPT1B | |
| SCHEMBL26657728 | 0.87 | CPT2 (0.64) | IDH1CPT2CPT1ACPT1B | |
| SCHEMBL26657739 | 0.86 | CPT2 (0.66) | IDH1CPT2CPT1ACPT1B | |
| SCHEMBL26657377 | 0.85 | RXFP1 (0.66) | IDH1THRBCPT2CPT1ACPT1B | |
| SCHEMBL26657301 | 0.85 | CPT2 (0.65) | IDH1CPT2CPT1ACPT1B | |
| SCHEMBL26658117 | 0.84 | IDH1 (0.58) | IDH1 | |
| SCHEMBL26656775 | 0.84 | IDH1 (0.67) | IDH1CPT2CPT1ACPT1B | |
| SCHEMBL26658104 | 0.84 | SMN1; SMN2 (0.69) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339851-A1 | CXCR6 SULFONAMIDE COMPOUNDS | CHEMOCENTRYX, INC. | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339851-A1 | CXCR6 SULFONAMIDE COMPOUNDS | CXCR6, CXCR1, CXCR2 | IDH1 2340/4885THRB 2259/4885CPT2 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.