SCHEMBL2665802

SCHEMBL2665802

CCc1ccc(-c2csc(N(Cc3ccc(C(=O)NCCC(=O)O)cc3)Cc3ccc(F)cc3F)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 20/20 0.55
GIPR P48546 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18674589 0.81 GCGR (0.63) GCGRGIPR
SCHEMBL2665826 0.80 GCGR (0.56) GCGRGIPR
SCHEMBL2665775 0.78 GCGR (0.77) GCGRGIPR
SCHEMBL2665865 0.76 GCGR (0.81) GCGRGIPR
SCHEMBL9071174 0.75 GCGR (0.53) GCGRGIPR
SCHEMBL2647303 0.74 GCGR (0.74) GCGRGIPR
SCHEMBL2648133 0.74 GCGR (0.74) GCGRGIPR
SCHEMBL2665855 0.74 GCGR (0.74) GCGRGIPR
SCHEMBL9071163 0.74 GCGR (0.61) GCGRGIPR
SCHEMBL2665864 0.74 GCGR (0.70) GCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004002480-A1 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed