SCHEMBL26658124

SCHEMBL26658124

c1cnc(-c2nccs2)nn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
PKM P14618 2/20 0.42
RECQL P46063 1/20 0.42
PDPK1 O15530 1/20 0.42
ADORA2A P29274 3/20 0.41
KMT2A Q03164 2/20 0.39
LOXL2 Q9Y4K0 1/20 0.37
CYP2A6 P11509 1/20 0.37
SMPD3 Q9NY59 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
HSP90AA1 P07900 1/20 0.36
TSHR P16473 1/20 0.36
NOS1 P29475 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ADRB2 P07550 1/20 0.34
FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL556950 0.77 PDPK1 (0.54) RAB9ANPC1PKMRECQLPDPK1
SCHEMBL102331 0.72 PDPK1 (0.59) RAB9APDPK1ADORA2ALOXL2CYP2A6
SCHEMBL29522058 0.72
SCHEMBL5553224 0.72
SCHEMBL28154527 0.70 PDPK1 (0.56) RAB9APDPK1ADORA2ALOXL2CYP2A6
SCHEMBL30632310 0.70 PDPK1 (0.56) RAB9APDPK1ADORA2ALOXL2CYP2A6
SCHEMBL30534095 0.70 PDPK1 (0.56) RAB9APDPK1ADORA2ALOXL2CYP2A6
SCHEMBL31556353 0.70 PDPK1 (0.56) RAB9APDPK1ADORA2ALOXL2CYP2A6
SCHEMBL16112970 0.68 PDPK1 (0.45) RAB9ANPC1PKMRECQLPDPK1
SCHEMBL3396700 0.68 PDPK1 (0.41) RAB9ANPC1PKMRECQLPDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4281119-A1 PRECURSOR MARKER AND RADIOTRACER FOR NUCLEAR-MEDICAL DIAGNOSIS AND THERAPY OF BONE-METASTATIC PROSTATE CANCER SCV - SpezialChemikalienVertrieb GmbH (DE) 2023-11-29 EP disclosed