Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413331 | 0.84 | L3MBTL1 (0.54) | MAPK1CA1CA2KDM4EL3MBTL1 | |
| SCHEMBL6413338 | 0.84 | L3MBTL1 (0.54) | MAPK1CA1CA2KDM4EL3MBTL1 | |
| SCHEMBL2665962 | 0.82 | KDM4E (0.54) | MAPK1CA1CA2KDM4EL3MBTL1 | |
| SCHEMBL6641242 | 0.82 | MAPK1 (0.51) | MAPK1KDM4EL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL6641237 | 0.82 | MAPK1 (0.51) | MAPK1KDM4EL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL2400709 | 0.81 | MAPT (0.62) | MAPK1CA1CA2KDM4EL3MBTL1 | |
| SCHEMBL30644141 | 0.81 | KMT2A (0.52) | MAPK1KDM4EL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL2400706 | 0.81 | MAPT (0.62) | MAPK1CA1CA2KDM4EL3MBTL1 | |
| SCHEMBL26643204 | 0.81 | KMT2A (0.52) | MAPK1KDM4EL3MBTL1PTPN1ALDH1A1 | |
| SCHEMBL4255769 | 0.81 | PTPN1 (0.71) | PTGS2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093535-A1 | Vinyl phenyl derivatives as GLK activators | ASTRAZENECA AB | 2007-04-26 | — | — | US | disclosed |
| US-20070093535-A1 | Vinyl phenyl derivatives as GLK activators | ASTRAZENECA AB | 2007-04-26 | — | — | US | disclosed |
| US-7199140-B2 | Vinyl phenyl derivatives as GLK activators | ASTRAZENECA AB (SE) | 2007-04-03 | — | — | US | disclosed |
| US-7199140-B2 | Vinyl phenyl derivatives as GLK activators | ASTRAZENECA AB (SE) | 2007-04-03 | — | — | US | disclosed |
| WO-2003000262-A1 | VINYL PHENYL DERIVATIVES AS GLK ACTIVATORS | ASTRAZENECA AB (SE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093535-A1 | Vinyl phenyl derivatives as GLK activators | GCK, GCKR, GK | MAPK1 565/4885PTGS2 291/4885CA12 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.