Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650034 | 0.85 | GCGR (0.57) | GCGRSMN1; SMN2KMT2AMEN1ADORA1 | |
| SCHEMBL2666078 | 0.78 | GCGR (0.41) | GCGRSMN1; SMN2TSHRMAPT | |
| SCHEMBL2665979 | 0.77 | GCGR (0.51) | GCGRSMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL13963391 | 0.69 | GCGR (0.38) | GCGRSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL13963028 | 0.65 | PTPN1 (0.43) | GCGRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2648406 | 0.65 | GCGR (0.70) | GCGRSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL13963500 | 0.65 | PIK3CD (0.36) | GCGRSMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL13963604 | 0.64 | ADORA1 (0.45) | GCGRADORA1 | |
| SCHEMBL34467553 | 0.63 | DYRK1A (0.46) | SMN1; SMN2KMT2AMEN1ADORA1MAPT | |
| SCHEMBL13963605 | 0.63 | PTPN1 (0.48) | GCGRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024066-A2 | METHOD OF TREATING DIABETES AND RELATED CONDITIONS | MERCK & CO., INC. (US) | 2004-03-25 | — | — | WO | disclosed |