Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648406 | 0.85 | GCGR (0.70) | GCGRMAPTPOLBHTTMAPK1 | |
| SCHEMBL9070769 | 0.80 | PDE4B (0.48) | PDE4BPDE4DTP53MAPTPOLB | |
| SCHEMBL2665980 | 0.77 | GCGR (0.42) | GCGRMAPTTSHRMEN1KMT2A | |
| SCHEMBL13963334 | 0.73 | GCGR (0.50) | GCGRPDE4BPDE4DTP53MAPT | |
| SCHEMBL4041573 | 0.73 | GCGR (0.61) | GCGRMAPTPOLBHTTLMNA | |
| SCHEMBL13963505 | 0.72 | GCGR (0.58) | GCGRTP53MAPTHTTNPC1 | |
| SCHEMBL13963028 | 0.72 | PTPN1 (0.43) | GCGRHTTLMNAMAPK1RAB9A | |
| Diethylamine SCHEMBL30417292 | 0.71 | TNF (0.57) | PDE4BPDE4DTP53MAPTPOLB | |
| SCHEMBL7929684 | 0.71 | PDE4B (0.55) | PDE4BPDE4DTP53TNIKMAPT | |
| SCHEMBL21247383 | 0.71 | MAPT (0.73) | PDE4BPDE4DTP53MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024066-A2 | METHOD OF TREATING DIABETES AND RELATED CONDITIONS | MERCK & CO., INC. (US) | 2004-03-25 | — | — | WO | disclosed |