Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 6/20 | 0.48 |
| ▸ | ADH1C | P00326 | 4/20 | 0.48 |
| ▸ | ADH4 | P08319 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807577 | 0.77 | TRPA1 (0.35) | TRPA1TRPM8EPHX1 | |
| Formic Acid SCHEMBL28687832 | 0.77 | TRPA1 (0.40) | TRPA1TRPM8EPHX1 | |
| Formamide SCHEMBL29160592 | 0.77 | EPHX1 (0.38) | TRPA1TRPM8EPHX1 | |
| SCHEMBL452781 | 0.76 | TRPA1 (0.39) | TRPA1TRPM8EPHX1 | |
| SCHEMBL1760669 | 0.76 | TRPA1 (0.39) | TRPA1TRPM8EPHX1 | |
| SCHEMBL7979 | 0.76 | TRPA1 (0.39) | TRPA1TRPM8EPHX1 | |
| SCHEMBL29136143 | 0.74 | EPHX1 (0.36) | TRPA1TRPM8EPHX1 | |
| Water SCHEMBL2851760 | 0.73 | TRPA1 (0.37) | TRPA1TRPM8EPHX1 | |
| Hydrochloric Acid SCHEMBL6863594 | 0.73 | TRPA1 (0.37) | TRPA1TRPM8EPHX1 | |
| Charcoal, Activated SCHEMBL4530459 | 0.73 | TRPA1 (0.37) | TRPA1TRPM8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066145-A1 | HETEROARYL-UREAS AND THEIR USE AS GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-07-21 | — | — | WO | disclosed |