Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 12/20 | 0.51 |
| ▸ | TSHR | P16473 | 9/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30672423 | 0.88 | CYP3A4 (0.46) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30672389 | 0.88 | CYP3A4 (0.46) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30672465 | 0.88 | CYP3A4 (0.46) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL26662873 | 0.83 | SYK (0.49) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8267044 | 0.83 | CYP3A4 (0.52) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL31045519 | 0.83 | CYP3A4 (0.52) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL26662885 | 0.82 | SYK (0.48) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15149564 | 0.81 | CYP3A4 (0.50) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL20299871 | 0.81 | CYP3A4 (0.50) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL21800943 | 0.81 | CYP3A4 (0.50) | CYP3A4TSHRCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346602-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA INC (US) | 2025-11-13 | — | — | US | disclosed |
| EP-4525987-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023225664-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346602-A1 | LACTAM SUBSTITUTED IMIDAZOPYRIDAZINE IL-17A MODULATORS AND USES THEREOF | IL17A, IL15, IL18 | CYP3A4 95/4885TSHR 4436/4885CYP2C9 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.