Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 6/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666697 | 0.92 | TDP1 (0.33) | GCKPLAU | |
| SCHEMBL13209323 | 0.88 | GCK (0.42) | GCK | |
| SCHEMBL13209296 | 0.88 | GCK (0.42) | GCK | |
| SCHEMBL2669305 | 0.85 | GCK (0.32) | GCK | |
| SCHEMBL2666564 | 0.85 | GCK (0.43) | GCK | |
| SCHEMBL13209318 | 0.83 | GCK (0.34) | GCK | |
| SCHEMBL2666718 | 0.78 | GCK (0.38) | GCK | |
| SCHEMBL19792903 | 0.76 | CA12 (0.51) | GCKACACB | |
| SCHEMBL13209552 | 0.75 | GCK (0.38) | GCK | |
| SCHEMBL13209325 | 0.73 | GCK (0.51) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040528-A1 | PHENOXY BENZAMIDE COMPOUNDS WITH UTILITY IN THE TREATMENT OF TYPE 2 DIABETES AND OBESITY | ASTRAZENECA AB (SE) | 2006-04-20 | — | — | WO | disclosed |