Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548093 | 0.96 | CA2 (0.36) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL12501660 | 0.92 | CA2 (0.38) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL23227787 | 0.88 | CA2 (0.36) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL12597475 | 0.87 | HDAC3 (0.32) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL22750792 | 0.86 | KDM4E (0.40) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL17839065 | 0.81 | CA2 (0.33) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL3857896 | 0.81 | CA2 (0.35) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL17839117 | 0.81 | CA2 (0.33) | CA2CA1SMYD2CYP3A4HTT | |
| SCHEMBL3290837 | 0.79 | CYP24A1 (0.40) | CA1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL31645157 | 0.78 | SMYD2 (0.33) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4281463-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | JANSSEN Pharmaceutica NV (BE) | 2023-11-29 | — | — | EP | disclosed |
| WO-2022159976-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | ANAKURIA THERAPEUTICS, INC. (US) | 2022-07-28 | — | — | WO | disclosed |
| CN-109982992-B | Method for preparing eldecalcitol and intermediate for same | 研成精密化学株式会社 | 2022-05-17 | — | — | CN | disclosed |