Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.36 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24301584 | 1.00 | UTS2R (0.38) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL26902789 | 0.93 | HDAC1 (0.36) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29025544 | 0.93 | UTS2R (0.39) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29025548 | 0.93 | UTS2R (0.39) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24301582 | 0.93 | PDE4A (0.41) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24301580 | 0.93 | PDE4A (0.41) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29717153 | 0.93 | PDE4A (0.41) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24302112 | 0.92 | HDAC3 (0.36) | PDE4APDE4BPDE4CPDE4DPADI6 | |
| SCHEMBL24302411 | 0.88 | PDE4A (0.36) | UTS2RPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29717165 | 0.88 | PDE4A (0.36) | UTS2RPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381146-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2023-11-30 | — | — | US | disclosed |
| EP-4225743-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | Helios Huaming Biopharma Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| WO-2022078294-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381146-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | SSB, BTK, PADI6 | UTS2R 2090/4885PDE4A 56/4885PDE4B 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.