Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10230984 | 0.90 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL10231004 | 0.90 | GCK (0.45) | GCKKCNH2KMT2ACLK1 | |
| SCHEMBL10230994 | 0.90 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL9072364 | 0.89 | GCK (0.45) | GCKKCNH2KMT2A | |
| SCHEMBL2666751 | 0.88 | GCK (0.44) | GCKKCNH2KMT2A | |
| SCHEMBL10230964 | 0.88 | GCK (0.46) | GCKKCNH2KMT2A | |
| SCHEMBL10230968 | 0.88 | GCK (0.46) | GCKKCNH2KMT2A | |
| SCHEMBL10230961 | 0.88 | GCK (0.44) | GCKKCNH2KMT2A | |
| SCHEMBL2666983 | 0.87 | GCK (0.43) | GCKKCNH2KMT2A | |
| SCHEMBL2666752 | 0.87 | GCK (0.43) | GCKKCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007886-A1 | AN OXIME DERIVATIVE AND PREPARATIONS THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-18 | — | — | WO | disclosed |