SCHEMBL26669195

SCHEMBL26669195

CCCOCCOCCNC(=O)NC

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 6/20 0.51
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.38
EPHX1 P07099 5/20 0.38
PIK3CG P48736 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24286829 0.98 EPHX2 (0.53) EPHX2MEN1KMT2AEPHX1PIK3CG
SCHEMBL13411699 0.92 KMT2A (0.52) EPHX2MEN1KMT2ASMN1; SMN2EPHX1
SCHEMBL14984056 0.90 EPHX1 (0.47) EPHX2MEN1KMT2ASMN1; SMN2EPHX1
SCHEMBL19171879 0.89 KMT2A (0.48) EPHX2MEN1KMT2ASMN1; SMN2EPHX1
SCHEMBL14493540 0.87 EPHX2 (0.57) EPHX2MEN1KMT2AEPHX1PIK3CG
SCHEMBL19636157 0.87 EPHX2 (0.54) EPHX2EPHX1MAPTHSD17B10KEAP1
SCHEMBL19171981 0.86 MEN1 (0.44) EPHX2MEN1KMT2ASMN1; SMN2EPHX1
SCHEMBL6286871 0.86 KMT2A (0.47) EPHX2MEN1KMT2ASMN1; SMN2HSD17B10
SCHEMBL26669049 0.86 EPHX2 (0.53) EPHX2MEN1KMT2ASMN1; SMN2EPHX1
SCHEMBL26668866 0.86 EPHX2 (0.53) EPHX2MEN1KMT2ASMN1; SMN2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4265608-A1 BENZOHETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) 2023-10-25 EP disclosed