SCHEMBL6286871

SCHEMBL6286871

CNCCOCCOCCNC(=O)NC

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.39
EPHX2 P34913 5/20 0.38
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
FBP1 P09467 1/20 0.36
MTNR1A P48039 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290526 0.98 KMT2A (0.44) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL13411699 0.94 KMT2A (0.52) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL19171879 0.91 KMT2A (0.48) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL6290245 0.86 MEN1 (0.46) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL19593906 0.86 KMT2A (0.46) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL26669195 0.86 EPHX2 (0.51) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL19607948 0.86 MEN1 (0.46) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL19171981 0.84 MEN1 (0.44) KMT2AMEN1SMN1; SMN2EPHX2KEAP1
SCHEMBL14984056 0.84 EPHX1 (0.47) KMT2AMEN1SMN1; SMN2EPHX2MTNR1A
SCHEMBL6289746 0.84 MEN1 (0.44) KMT2AMEN1SMN1; SMN2EPHX2FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed