Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 2/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21872548 | 0.87 | ABL1 (0.38) | AHCYADKDOT1LABL1KDR | |
| SCHEMBL24965973 | 0.84 | AHCY (0.42) | AHCYADKDOT1LABL1KDR | |
| SCHEMBL25842029 | 0.81 | KDR (0.48) | ABL1KDRRETLCKSRC | |
| SCHEMBL21127826 | 0.80 | LRRK2 (0.58) | ADKDOT1LABL1KDRMAP4K4 | |
| SCHEMBL25842045 | 0.79 | FGFR2 (0.35) | ADKKDRRETFGFR1 | |
| SCHEMBL22327073 | 0.77 | RET (0.37) | CLK4RETLCKCDK5SRC | |
| SCHEMBL13314374 | 0.75 | ABL1 (0.51) | ADKDOT1LABL1KDRMAP4K4 | |
| SCHEMBL20810788 | 0.71 | LRRK2 (0.39) | ADKDOT1LABL1KDRMAP4K4 | |
| SCHEMBL130452 | 0.71 | PIK3CD (0.46) | AHCYABL1KDRRETSRC | |
| SCHEMBL16361030 | 0.71 | LRRK2 (0.39) | ADKABL1KDRMAP4K4PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212369-A1 | NUCLEOTIDE CYCLIC CLEAVABLE MOIETIES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230340592-A1 | TARGETED SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-10-26 | — | — | US | disclosed |