Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31507314 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LCKFYNMAPK1SMN1; SMN2 | |
| SCHEMBL26670660 | 0.86 | POLB (0.41) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL27611644 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL3723790 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPK1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL6262091 | 0.80 | SMN1; SMN2 (0.38) | ALDH1A1MAPK1SMN1; SMN2CA9MEN1 | |
| SCHEMBL23583482 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPK1SMN1; SMN2CA12CA1 | |
| SCHEMBL29198823 | 0.76 | POLQ (0.43) | ALDH1A1LCKFYNCA12CA1 | |
| SCHEMBL31128181 | 0.74 | NQO2 (0.41) | ALDH1A1L3MBTL1HPGDPOLB | |
| SCHEMBL20564431 | 0.74 | CA12 (0.57) | ALDH1A1LCKFYNMAPK1SMN1; SMN2 | |
| SCHEMBL27606177 | 0.72 | POLB (0.41) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4532486-A1 | PYRIDINE CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | Boundless Bio, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023230477-A1 | PYRIDINE CHECKPOINT KINASE 1 (CHK1) INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. (US) | 2023-11-30 | — | — | WO | disclosed |