Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 3/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | GCK | P35557 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667145 | 0.89 | GCK (0.41) | CPT1ACPT1BACACBGCKKCNH2 | |
| SCHEMBL1775504 | 0.88 | GCK (0.48) | CPT1ACPT1BACACBGCKKCNH2 | |
| SCHEMBL9072424 | 0.82 | GCK (0.41) | ACACBGCKKCNH2 | |
| SCHEMBL1776034 | 0.79 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL2667132 | 0.79 | ACACB (0.40) | CPT1ACPT1BACACBALPL | |
| SCHEMBL2667144 | 0.79 | ACACB (0.39) | CPT1ACPT1BACACBALPL | |
| SCHEMBL1776159 | 0.78 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL1776632 | 0.77 | GCK (0.48) | GCKKCNH2 | |
| SCHEMBL1775130 | 0.77 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL1775249 | 0.76 | GCK (0.57) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125972-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |