Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776034 | 0.90 | GCK (0.54) | GCKKCNH2 | |
| SCHEMBL2667142 | 0.89 | CPT1A (0.36) | GCKKCNH2CPT1ACPT1BACACB | |
| SCHEMBL1776159 | 0.88 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL9072424 | 0.87 | GCK (0.41) | GCKKCNH2ACACB | |
| SCHEMBL1775249 | 0.86 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL1774772 | 0.86 | GCK (0.59) | GCKKCNH2 | |
| SCHEMBL2667132 | 0.83 | ACACB (0.40) | CPT1ACPT1BACACB | |
| SCHEMBL2667144 | 0.83 | ACACB (0.39) | CPT1ACPT1BACACB | |
| SCHEMBL1775130 | 0.81 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL1775166 | 0.79 | GCK (0.49) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125972-A1 | HETEROARYL BENZAMIDE DERIVATIVES FOR USE AS GLK ACTIVATORS IN THE TREATMENT OF DIABETES | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |