Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15655284 | 0.77 | AXL (0.40) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL34461816 | 0.77 | AXL (0.40) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL15654873 | 0.77 | AXL (0.48) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL14369942 | 0.73 | SRC (0.46) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL15736808 | 0.72 | SPR (0.46) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL17305955 | 0.70 | PDPK1 (0.40) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL29631094 | 0.69 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL21393430 | 0.69 | AXL (0.44) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL14266837 | 0.69 | AXL (0.48) | PDPK1PARP1AXLMKNK1MKNK2 | |
| SCHEMBL15883606 | 0.68 | KDM4E (0.39) | PDPK1PARP1ADORA2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117381-A2 | 2 -AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2007-10-18 | — | — | WO | disclosed |