⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878754 | 0.78 | TSHR (0.55) | — | |
| SCHEMBL27380 | 0.75 | TSHR (1.00) | — | |
| SCHEMBL5311581 | 0.75 | TSHR (1.00) | — | |
| SCHEMBL177923 | 0.75 | TSHR (0.67) | — | |
| SCHEMBL666545 | 0.74 | TSHR (0.57) | — | |
| SCHEMBL8854785 | 0.74 | TSHR (0.57) | — | |
| SCHEMBL9795394 | 0.73 | TSHR (0.94) | — | |
| Methane SCHEMBL11192510 | 0.73 | TSHR (0.94) | — | |
| SCHEMBL9725547 | 0.73 | TSHR (0.94) | — | |
| SCHEMBL1009266 | 0.73 | TSHR (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118750465-A | Preparation method and application of fluorine-containing lipid nanoparticle | 中国科学院精密测量科学与技术创新研究院 | 2024-10-11 | — | — | CN | claimed |
| CN-118084634-A | Preparation method of fluorine-containing ether and fluorine-containing ether | 纯钧新材料(深圳)有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117486852-A | Fluorine-containing rotaxane molecule and preparation method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2024-02-02 | — | — | CN | claimed |
| CN-116799311-A | Ether electrolyte and lithium metal battery | 华中科技大学 | 2023-09-22 | — | — | CN | claimed |
| CN-115106085-B | Application of composite photocatalyst in photocatalytic oxidation of aromatic alcohol coupling hydrogen | 中国科学院理化技术研究所 | 2023-09-15 | — | — | CN | claimed |
| CN-113797977-B | Ruthenium catalyst and application thereof | 沈阳中化农药化工研发有限公司 | 2022-11-29 | — | — | CN | claimed |
| CN-115106085-A | Application of composite photocatalyst in photocatalytic oxidation aromatic alcohol coupling hydrogen production | 中国科学院理化技术研究所 | 2022-09-27 | — | — | CN | claimed |
| CN-113797977-A | Ruthenium catalyst and application thereof | 沈阳中化农药化工研发有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-107827708-B | Method for preparing polyfluorobenzyl alcohol | 大连奇凯医药科技有限公司 | 2020-09-29 | — | — | CN | claimed |
| EP-3246328-B1 | QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2020-07-22 | — | — | EP | claimed |
| EP-3246328-A1 | QUINAZOLINE HETEROCYCLIC COMPOUND AS EGFR KINASE INHIBITOR, AND PREPARATION AND APPLICATION THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2017-11-22 | — | — | EP | claimed |
| CN-104254513-B | Process for separating aryl carboxylic acid | 瑞来斯实业公司 | 2017-03-22 | — | — | CN | claimed |
| CN-103694197-B | Phenoxyacetamide compound and preparation method and application thereof | UNIV HUAZHONG NORMAL | 2015-07-15 | — | — | CN | claimed |
| CN-104254513-A | Process for separating aryl carboxylic acid | RELIANCE IND LTD | 2014-12-31 | — | — | CN | claimed |
| CN-102015706-B | Imidazolidinone derivatives as 11B-HSD1 inhibitors | HOFFMANN LA ROCHE | 2014-07-16 | — | — | CN | claimed |
| CN-103694197-A | Phenoxyacetamide compound and preparation method and application thereof | UNIV HUAZHONG NORMAL | 2014-04-02 | — | — | CN | claimed |
| CN-101287692-B | Preparation method of optically active fluorobenzyl alcohol | CENTRAL GLASS CO LTD | 2012-06-06 | — | — | CN | claimed |
| CN-101287692-A | Preparation method of optically active fluorobenzyl alcohol | CENTRAL GLASS CO LTD (JP) | 2008-10-15 | — | — | CN | claimed |
| EP-0253536-A2 | Fluorobenzyl esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | claimed |
| US-4275250-A | CHEMICAL INTERMEDIATES FOR VINYLCYCLOPROPANE CARBOXYLIC ACID ESTERS OF HALOGENATED BENZYL ALCOHOL WHICH ARE ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-23 | — | — | US | claimed |