SCHEMBL27380

SCHEMBL27380

c1ccc(COCc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 1.00
IDO1 P14902 1/20 0.60
AGXT P21549 1/20 0.57
CA1 P00915 5/20 0.52
CA2 P00918 3/20 0.52
CA9 Q16790 3/20 0.52
CA7 P43166 2/20 0.52
KDM4E B2RXH2 1/20 0.52
POLB P06746 1/20 0.52
TACR1 P25103 2/20 0.50
CALM1 P0DP23 1/20 0.50
ALDH1A1 P00352 2/20 0.48
LMNA P02545 1/20 0.48
CYP1A2 P05177 1/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
CYP2C19 P33261 1/20 0.48
PTGS2 P35354 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HIF1A Q16665 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5311581 1.00 TSHR (1.00) TSHRIDO1AGXTCA1CA2
SCHEMBL9795394 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
Calcium SCHEMBL2864550 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
Water SCHEMBL15535487 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
SCHEMBL9491202 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
Methane SCHEMBL11192510 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
SCHEMBL10317949 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
Potassium SCHEMBL586337 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
SCHEMBL9725547 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2
SCHEMBL1009266 0.97 TSHR (0.94) TSHRIDO1AGXTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 50358 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-224271196-U Benzyl ether synthesis reaction kettle Hubei Xinxuanhong New Material Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122076530-A Fct-phase NiPd nanoparticle catalyst and preparation method and application thereof 2026-05-26 CN claimed
CN-122085595-A Colored photosensitive resin composition and application thereof 2026-05-26 CN claimed
CN-122085594-A Positive coloring photosensitive composition and application thereof 2026-05-26 CN claimed
CN-122071003-A Preparation method of copper-palladium alloy loaded nano titanium dioxide material for producing methane by photocatalytic carbon dioxide reduction 华东理工大学 2026-05-22 CN claimed
CN-117304016-B Catalytic oxidation cracking method for aromatic ether substances 郑州大学 2026-05-22 CN claimed
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
WO-2026101568-A1 MODIFIED REPEAT UNIT FOR ENHANCED INTERACTION ENERGY AND THERMAL STABILITY OF HIGH TEMPERATURE LUBRICANTS FOR MAGNETIC MEDIA WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2026-05-15 WO claimed
US-12624060-B2 Ruthenium complexes, methods of their preparation and application thereof in olefin cross metathesis APEIRON SYNTHESIS S.A. (PL) 2026-05-12 US claimed
US-20260125611-A1 MODIFIED REPEAT UNIT FOR ENHANCED INTERACTION ENERGY AND THERMAL STABILITY OF HIGH TEMPERATURE LUBRICANTS FOR MAGNETIC MEDIA WESTERN DIGITAL TECH INC (US) 2026-05-07 US claimed
US-4049733-A Synthesis of diphenylmethane using phosphoric-sulfuric acid catalyst UOP INC. (US) 1977-09-20 US claimed
US-4041712-A CATIONIC EMULSION OF PETROLEUM ASPHALT, NONIONIC SURFACTANTS, ELASTOMERS THE FLINTKOTE COMPANY (US) 1977-08-16 US claimed
US-4039587-A Method of preparing polynuclear, halogenated, aromatic benzyl ethers DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-08-02 US claimed
US-4025578-A Elastomeric liquid polymer vulcanizates from epoxy resin, liquid carboxy terminated polymer, dihydric phenol, and an amine THE B. F. GOODRICH COMPANY (US) 1977-05-24 US claimed
US-4014845-A Fugitive vehicle system OWENS-ILLINOIS, INC. (US) 1977-03-29 US claimed
US-4000087-A DYE PRECURSORS IN POLYAMIDE SHELLS; INCORPORATION OF POLYSTYRENE OR EPOXY RESINS IN THE FILL MATERIAL MOORE BUSINESS FORMS, INC. (US) 1976-12-28 US claimed
US-3997708-A ADDITION PHILLIPS PETROLEUM COMPANY (US) 1976-12-14 US claimed
US-3979916-A Product and method for reducing water loss through soil by seepage THE FLINTKOTE COMPANY (US) 1976-09-14 US claimed
US-3963852-A Clay-coated record material of improved image durability MOORE BUSINESS FORMS, INC. (US) 1976-06-15 US claimed
US-3957825-A PROCESS FOR SYNTHESIZING ZEARALANONE AND RELATED COMPOUNDS COMMERCIAL SOLVENTS CORPORATION (US) 1976-05-18 US claimed