Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GCK | P35557 | 4/20 | 0.42 |
| ▸ | AQP4 | P55087 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070874 | 0.83 | RAB9A (0.59) | RAB9ALMNANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9070820 | 0.79 | RAB9A (0.49) | RAB9ALMNANPC1SMN1; SMN2KDM4E | |
| SCHEMBL2667596 | 0.79 | RAB9A (0.49) | RAB9ALMNANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9070891 | 0.79 | NOX1 (0.49) | RAB9ALMNASMN1; SMN2KDM4EGCK | |
| SCHEMBL9070883 | 0.79 | NOX1 (0.49) | RAB9ALMNASMN1; SMN2KDM4EGCK | |
| SCHEMBL2667626 | 0.79 | NOX1 (0.49) | RAB9ALMNASMN1; SMN2KDM4EGCK | |
| SCHEMBL9070878 | 0.78 | RAB9A (0.51) | RAB9ALMNANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9070877 | 0.78 | RAB9A (0.51) | RAB9ALMNANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9070881 | 0.78 | RAB9A (0.51) | RAB9ALMNANPC1SMN1; SMN2KDM4E | |
| SCHEMBL9070805 | 0.78 | RAB9A (0.50) | RAB9ALMNANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |