Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226979 | 0.87 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| SCHEMBL14033906 | 0.87 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| SCHEMBL27048103 | 0.86 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| SCHEMBL27048362 | 0.86 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| SCHEMBL14033908 | 0.86 | CYP2D6 (0.54) | HRH3OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL21831282 | 0.86 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| Hydrochloric Acid SCHEMBL27130665 | 0.84 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| Hydrochloric Acid SCHEMBL27033984 | 0.84 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| Hydrochloric Acid SCHEMBL27033977 | 0.84 | HRH3 (0.43) | HRH3ACHEOPRM1OPRD1SLC6A2 | |
| SCHEMBL6874564 | 0.83 | HRH3 (0.42) | HRH3ACHEOPRM1OPRD1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814348-B9 | SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2023-11-01 | — | — | EP | disclosed |