Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.55 |
| ▸ | GIPR | P48546 | 6/20 | 0.55 |
| ▸ | GLP1R | P43220 | 2/20 | 0.38 |
| ▸ | GCG | P01275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667299 | 0.86 | GCGR (0.61) | GCGRGIPRGLP1R | |
| SCHEMBL12360391 | 0.84 | GCGR (0.59) | GCGRGIPRGLP1R | |
| SCHEMBL2667403 | 0.84 | GCGR (0.64) | GCGRGIPRGLP1R | |
| SCHEMBL2667290 | 0.84 | GCGR (0.62) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2667404 | 0.83 | GCGR (0.54) | GCGRGIPR | |
| SCHEMBL2667293 | 0.82 | GCGR (0.57) | GCGRGIPRGLP1RGCG | |
| SCHEMBL2667910 | 0.82 | GCGR (0.62) | GCGRGIPRGLP1R | |
| SCHEMBL12360394 | 0.80 | GCGR (0.76) | GCGRGIPR | |
| SCHEMBL2667296 | 0.80 | GCGR (0.57) | GCGRGIPR | |
| SCHEMBL13003164 | 0.79 | GCGR (0.69) | GCGRGIPRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069158-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-08-19 | — | — | WO | disclosed |