Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 15/20 | 0.73 |
| ▸ | GIPR | P48546 | 5/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | DDHD2 | O94830 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252023 | 0.92 | GCGR (0.77) | GCGRGIPRDDHD2P2RX3DAGLB | |
| SCHEMBL2252928 | 0.85 | GCGR (0.66) | GCGRGIPRABL1BCRDDHD2 | |
| SCHEMBL2667522 | 0.85 | GCGR (1.00) | GCGRGIPR | |
| SCHEMBL9071550 | 0.84 | GCGR (0.68) | GCGRGIPRDDHD2HDAC1 | |
| SCHEMBL9071590 | 0.83 | GCGR (0.78) | GCGRGIPR | |
| SCHEMBL2667495 | 0.83 | GCGR (0.70) | GCGRGIPRDDHD2 | |
| SCHEMBL2250289 | 0.83 | GCGR (0.63) | GCGRGIPRABL1BCRDDHD2 | |
| SCHEMBL2667893 | 0.82 | GCGR (1.00) | GCGRGIPR | |
| SCHEMBL12360097 | 0.82 | GCGR (0.73) | GCGRGIPR | |
| SCHEMBL2251811 | 0.82 | GCGR (0.76) | GCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069158-A2 | SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-08-19 | — | — | WO | disclosed |