SCHEMBL2667495

SCHEMBL2667495

N=NNC(=N)NC(=O)c1ccc(Cc2cc(-c3ccc(OC(F)(F)F)cc3)nn2C2CCCCC2)cc1

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GCGR P47871 19/20 0.70
GIPR P48546 7/20 0.47
DDHD2 O94830 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9071550 0.88 GCGR (0.68) GCGRGIPRDDHD2
SCHEMBL2252023 0.84 GCGR (0.77) GCGRGIPRDDHD2
SCHEMBL2667494 0.83 GCGR (0.73) GCGRGIPRDDHD2
SCHEMBL2667522 0.83 GCGR (1.00) GCGRGIPR
SCHEMBL2667893 0.81 GCGR (1.00) GCGRGIPR
SCHEMBL9071590 0.81 GCGR (0.78) GCGRGIPR
SCHEMBL12360097 0.80 GCGR (0.73) GCGRGIPR
SCHEMBL2251811 0.80 GCGR (0.76) GCGRGIPR
SCHEMBL2252928 0.79 GCGR (0.66) GCGRGIPRDDHD2
SCHEMBL2250289 0.76 GCGR (0.63) GCGRGIPRDDHD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004069158-A2 SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE MERCK & CO., INC. (US) 2004-08-19 WO disclosed