Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070946 | 0.93 | GCK (0.62) | GCKKCNH2ALDH1A1 | |
| SCHEMBL2667645 | 0.93 | GCK (0.62) | GCKKCNH2ALDH1A1 | |
| SCHEMBL2667769 | 0.87 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL9071011 | 0.86 | ALDH1A1 (0.56) | GCKKCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL2667649 | 0.86 | GCK (0.79) | GCKKCNH2 | |
| SCHEMBL9070848 | 0.86 | GCK (0.64) | GCKKCNH2 | |
| SCHEMBL2667547 | 0.85 | GCK (0.67) | GCKKCNH2 | |
| SCHEMBL2667565 | 0.84 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL9071014 | 0.84 | GCK (0.61) | GCK | |
| SCHEMBL2667364 | 0.84 | TSHR (0.62) | GCKALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |