Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667651 | 0.90 | GCK (0.46) | GCKPTGESALOX5SCDMEN1 | |
| SCHEMBL9070795 | 0.87 | GCK (0.47) | GCKPTGESALOX5MAPK1LMNA | |
| SCHEMBL9070964 | 0.84 | GCK (0.50) | GCKPTGESALOX5MAPK1HTT | |
| SCHEMBL9070793 | 0.82 | SCD (0.55) | MAPK1HTTSCDCSNK2A2CSNK2B | |
| SCHEMBL9070963 | 0.81 | GCK (0.52) | GCKPTGESALOX5SCDMEN1 | |
| SCHEMBL2667661 | 0.80 | NPC1 (0.54) | GCKHTTSCDMEN1KMT2A | |
| SCHEMBL2667643 | 0.80 | RAB9A (0.49) | GCKPTGESALOX5MAPK1HTT | |
| SCHEMBL9070971 | 0.78 | GCK (0.53) | GCKPTGESALOX5MAPK1LMNA | |
| SCHEMBL9070970 | 0.77 | GCK (0.51) | GCKPTGESALOX5LNPEPLMNA | |
| SCHEMBL2667667 | 0.77 | NPC1 (0.51) | GCKSCDMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |