Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GCK | P35557 | 11/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CPT1A | P50416 | 2/20 | 0.44 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9071011 | 0.94 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1TSHRCYP1A2 | |
| SCHEMBL2667578 | 0.94 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPK1TSHRCYP1A2 | |
| SCHEMBL2667684 | 0.92 | ALDH1A1 (0.65) | ALDH1A1LMNAMAPK1TSHRCYP1A2 | |
| SCHEMBL2667389 | 0.92 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPK1TSHRCYP1A2 | |
| SCHEMBL2667577 | 0.91 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1TSHRCYP1A2 | |
| SCHEMBL2668002 | 0.90 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPK1TSHRCYP1A2 | |
| SCHEMBL2667683 | 0.89 | GCK (0.63) | GCKKCNH2 | |
| SCHEMBL2667535 | 0.88 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL9071058 | 0.87 | GCK (0.53) | GCKKCNH2 | |
| SCHEMBL9070850 | 0.87 | GCK (0.52) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |