Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 2/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667671 | 0.88 | GRM5 (0.48) | SCDRAB9ANPC1MAPT | |
| SCHEMBL2667648 | 0.87 | GRM5 (0.46) | MAPK1HTTSCDALDH1A1PDE5A | |
| SCHEMBL2667659 | 0.86 | SCD (0.50) | MAPK1HTTSCDALDH1A1PDE5A | |
| SCHEMBL2667666 | 0.85 | SCD (0.48) | SCDALDH1A1PDE5AKDM4ELMNA | |
| SCHEMBL2667670 | 0.83 | GCK (0.54) | MAPK1RAB9ANPC1MAPT | |
| SCHEMBL2667590 | 0.83 | MAPK1 (0.47) | MAPK1HTTSCDALDH1A1PDE5A | |
| SCHEMBL9071000 | 0.83 | KDM4E (0.50) | MAPK1HTTSCDALDH1A1PDE5A | |
| SCHEMBL2667707 | 0.82 | RAB9A (0.44) | ALDH1A1KDM4ERAB9ANPC1LMNA | |
| SCHEMBL9070809 | 0.81 | MAPK1 (0.45) | MAPK1HTTSCDALDH1A1PDE5A | |
| SCHEMBL9071045 | 0.81 | CPT1A (0.43) | MAPK1HTTSCDPDE5ACPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |