Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.54 |
| ▸ | STK25 | O00506 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2668004 | 0.98 | GCK (0.56) | GCKKCNH2STK25 | |
| SCHEMBL9070942 | 0.89 | GCK (0.49) | GCKKCNH2STK25 | |
| SCHEMBL9071056 | 0.88 | GCK (0.59) | GCKKCNH2 | |
| SCHEMBL2667365 | 0.85 | GCK (0.49) | GCKKCNH2STK25MEN1GAA | |
| SCHEMBL2667709 | 0.85 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL2667775 | 0.85 | CCNA2 (0.45) | GCKMEN1GAAKMT2A | |
| SCHEMBL2667654 | 0.84 | GCK (0.47) | GCKKCNH2 | |
| SCHEMBL9070995 | 0.84 | GCK (0.40) | GCK | |
| SCHEMBL9070834 | 0.83 | GCK (0.57) | GCKKCNH2 | |
| SCHEMBL9070927 | 0.82 | SMN1; SMN2 (0.42) | GCKHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |