Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070995 | 0.91 | GCK (0.40) | TP53SMN1; SMN2GCKMAPT | |
| SCHEMBL9071023 | 0.89 | GCK (0.54) | CCNA2CDK2CCNA1RAB9ANPC1 | |
| SCHEMBL9070927 | 0.89 | SMN1; SMN2 (0.42) | TP53SMN1; SMN2GCKLMNAKMT2A | |
| SCHEMBL2667654 | 0.89 | GCK (0.47) | CCNA2CDK2CCNA1RAB9ANPC1 | |
| SCHEMBL2667675 | 0.88 | GCK (0.52) | GCK | |
| SCHEMBL2667361 | 0.88 | BRD4 (0.42) | TP53GCKLMNAALDH1A1GAA | |
| SCHEMBL2667647 | 0.86 | GCK (0.44) | GCK | |
| SCHEMBL9071040 | 0.86 | GCK (0.48) | GCK | |
| SCHEMBL2667377 | 0.85 | ALDH1A1 (0.44) | RAB9ANPC1SMN1; SMN2GCKLMNA | |
| SCHEMBL2667549 | 0.85 | JAK2 (0.44) | RAB9ANPC1SMN1; SMN2GCKADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |