Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LOX | P28300 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667760 | 0.93 | GCK (0.44) | GCKMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2667809 | 0.93 | GCK (0.53) | GCKMEN1KMT2A | |
| SCHEMBL2667776 | 0.91 | GCK (0.51) | GCKMEN1KMT2A | |
| SCHEMBL9070996 | 0.90 | GCK (0.50) | GCK | |
| SCHEMBL2667360 | 0.89 | LMNA (0.45) | GCK | |
| SCHEMBL2667442 | 0.87 | GCK (0.57) | GCK | |
| SCHEMBL2667620 | 0.87 | GCK (0.46) | GCK | |
| SCHEMBL9071038 | 0.86 | GCK (0.48) | GCK | |
| SCHEMBL2667562 | 0.86 | GCK (0.47) | GCK | |
| SCHEMBL2667633 | 0.86 | GCK (0.53) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |