Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667781 | 0.92 | GCK (0.50) | GCKKCNH2GRM5 | |
| SCHEMBL9070991 | 0.90 | GCK (0.52) | GCKKCNH2 | |
| SCHEMBL9071024 | 0.90 | GCK (0.48) | GCKKCNH2 | |
| SCHEMBL9071020 | 0.89 | GCK (0.49) | GCKKCNH2 | |
| SCHEMBL2667786 | 0.88 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL2667585 | 0.84 | GCK (0.58) | GCKKCNH2GRM5 | |
| SCHEMBL2667811 | 0.84 | GCK (0.58) | GCKKCNH2GRM5 | |
| SCHEMBL2667969 | 0.84 | GCK (0.51) | GCKKCNH2 | |
| SCHEMBL2667348 | 0.84 | GCK (0.59) | GCKKCNH2GRM5 | |
| SCHEMBL9071058 | 0.84 | GCK (0.53) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |