Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 9/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667815 | 0.92 | MAPK1 (0.57) | GCKMAPK1SMN1; SMN2 | |
| SCHEMBL2667697 | 0.91 | GCK (0.49) | GCKKCNH2MAPK1GRM5RAB9A | |
| SCHEMBL2667580 | 0.91 | GCK (0.50) | GCKKCNH2GRM5RARGRAB9A | |
| SCHEMBL2667538 | 0.91 | GCK (0.50) | GCKKCNH2GRM5RARGRAB9A | |
| SCHEMBL2667564 | 0.91 | GCK (0.53) | GCKMAPK1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL2657219 | 0.90 | GCK (0.62) | GCKKCNH2MAPK1GRM5RARG | |
| SCHEMBL9071021 | 0.88 | GCK (0.51) | GCKKCNH2MAPK1GRM5RAB9A | |
| SCHEMBL9071061 | 0.86 | GCK (0.54) | GCKKCNH2MAPK1GRM5RARG | |
| SCHEMBL2667999 | 0.85 | MAPT (0.49) | GCKKCNH2MAPK1GRM5RAB9A | |
| SCHEMBL2668009 | 0.84 | GRM5 (0.48) | GCKKCNH2MAPK1GRM5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |