Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667589 | 0.93 | GCK (0.67) | GCKKCNH2 | |
| SCHEMBL13891603 | 0.88 | GCK (0.73) | GCKKCNH2RARG | |
| SCHEMBL1146914 | 0.88 | GCK (0.73) | GCKKCNH2RARG | |
| SCHEMBL2667711 | 0.86 | GCK (0.60) | GCKKCNH2 | |
| SCHEMBL944565 | 0.85 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2667664 | 0.85 | GCK (0.61) | GCKKCNH2 | |
| SCHEMBL2667559 | 0.84 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL2667973 | 0.83 | GCK (0.77) | GCKKCNH2 | |
| SCHEMBL2667788 | 0.82 | GCK (0.71) | GCKKCNH2 | |
| SCHEMBL9071063 | 0.82 | GCK (0.80) | GCKRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |