Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667791 | 0.91 | MAPT (0.56) | GCKKCNH2MAPK1MAPT | |
| SCHEMBL2667999 | 0.87 | MAPT (0.49) | GCKKCNH2KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL2667724 | 0.86 | KDM4E (0.50) | GCKKDM4ESMN1; SMN2PDE5AMAPK1 | |
| SCHEMBL9071061 | 0.85 | GCK (0.54) | GCKKCNH2KDM4EPDE5AMAPK1 | |
| SCHEMBL9071021 | 0.85 | GCK (0.51) | GCKKCNH2KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL2668000 | 0.84 | MAPT (0.63) | GCKKCNH2SMN1; SMN2MAPK1MAPT | |
| SCHEMBL2668007 | 0.84 | GCK (0.59) | GCKKCNH2 | |
| SCHEMBL2667580 | 0.84 | GCK (0.50) | GCKKCNH2KDM4ESMN1; SMN2GRM5 | |
| SCHEMBL2667538 | 0.84 | GCK (0.50) | GCKKCNH2KDM4ESMN1; SMN2GRM5 | |
| SCHEMBL2667578 | 0.83 | ALDH1A1 (0.54) | GCKKCNH2KDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083553-A1 | AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS | RHEOSCIENCE A/S (DK) | 2009-07-09 | — | — | WO | disclosed |