Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339398 | 0.80 | GAA (0.63) | LCKFYNMAPK1GAANPSR1 | |
| SCHEMBL28278829 | 0.79 | LCK (0.47) | LCKFYNMAPK1GAANPSR1 | |
| SCHEMBL26679226 | 0.79 | POLB (0.59) | KMT2AKDM4EMEN1POLB | |
| SCHEMBL13469242 | 0.79 | LCK (0.58) | LCKFYNMAPK1GAANPSR1 | |
| SCHEMBL6313004 | 0.76 | F13A1 (0.49) | MAPK1KDM4EF13A1STING1POLB | |
| SCHEMBL7347616 | 0.76 | LCK (0.59) | LCKFYNMAPK1GAANPSR1 | |
| SCHEMBL25679319 | 0.76 | LCK (0.55) | LCKFYNMAPK1GAANPSR1 | |
| SCHEMBL7407867 | 0.76 | CTSD (0.57) | KMT2AKDM4EMEN1 | |
| SCHEMBL27788117 | 0.74 | POLB (0.60) | KMT2AMEN1POLB | |
| SCHEMBL1417516 | 0.74 | LCK (0.72) | LCKFYNMAPK1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522595-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | The Scripps Research Institute (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220559-A2 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-11-16 | — | — | WO | disclosed |